Evaluation on the changes of left ventricular structure and diastolic function in patients with essential hypertensions and left ventricular filling disorders by real-time three-dimensional echocardiography
نویسندگان
چکیده
Objective: To evaluate left ventricular mass (LVM) and diastolic function in hypertension patients by RealTime Three-Dimensional Echocardiograph (RT-3DE). Methods: A total of 50 healthy subjects (as control group) and 50 subjects with essential hypertension and left ventricular filling disorders (as hypertension group) were enrolled in the study, and partial general echocardiographic parameters of their 17 regional left ventricular wall were measured by RT-3DE, including regional stroke volume (rSV), regional end-diastolic volume (rEDV), regional peak filling rate (rPFR), left ventricular peak filling rate (LVPFR), left interventricular septum, early and late diastolic peak velocity (Ea, Aa) of basal lateral (their ratio Ea/Aa was calculated), stroke volume (SV), left ventricular ejection fraction (LVEF), LVM and left ventricular end-diastolic volume (LVEDV). Results: One hundred cases acquired real-time three-dimensional images with clear endocardium boundary and 17 regional volume-time curves. Compared with the control group, LVPFR, Ea and Ea/Aa decreased, LVEDV, LVM and left ventricular myocardial mass index (LVMI) increased in hypertension group, the differences were statistically significant (all P<0.001). The increase of LVM in hypertension group was positively correlated with that of LVEDV (r=0.913). Conclusion: Compared with the normal population, decrease of left ventricular diastolic function and regional left ventricular wall diastolic dysfunction appeared in patients with essential hypertensions and left ventricular filling disorders.
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